HEAD & NECK CANCER
Definition
-
- Cancers of the lip, mouth, nose, sinuses, pharynx, larynx, and (possibly) trachea.
- 90% are squamous cell carcinomas.
Signs and symptoms
- Throat lump.
- Sore throat and odynophagia.
- Dysarthria and dysphonia. A hoarse voice suggests laryngeal disease or lung cancer invading the recurrent laryngeal nerve.
- Earache
- Cough
- Leukoplakia: white areas of keratosis in the mouth or throat, which can be premalignant. Hairy leukoplakia is a non-malignant type caused by EBV in HIV patients.
- Weight loss.
- Epistaxis
- Cervical lymphadenopathy: cervical nodes are a common site of spread. Supraclavicular lymphadenopathy suggests GI or lung cancer.
Risk factors
- UV light: lip cancer.
- HPV: oropharyngeal cancer.
- EBV: nasopharyngeal cancer.
- Alcohol
- Having a Drag i.e. smoking, especially oral and laryngeal cancer.
Adenocarcinomas:- Furniture factory workers are at increased risk due to wood dust exposure. Usually affects ethmoidal sinus.
Investigations
- Nasopharyngoscopy
- Needle biopsy including of lymph nodes.
- MRI for staging.
Management
- Radiotherapy is mainstay, especially if small.
- Many will also need surgery ± adjuvant chemotherapy.
The Polio Vaccine Menace: Should You Worry? There has been a recent spurt in media regarding the contamination of oral polio vaccine with type 2 poliovirus strain by a certain vaccine manufacturer. The Director of the Company was arrested last Friday after the CDSCO and Ministry of Health and Family Welfare lodged an FIR. What are the facts around it? Is it really something to worry about? Does the campaign “ DO BOOND JINDAGI KI ” for compulsory polio vaccination of kids require further investigation? We understand the concern. This made us consult the experts and find the answers. What is the Background of Type 2 Polio Virus Strain? Polio vaccines were prepared using three poliovirus strains: types 1, 2 and 3, in the past. However, August 2016 onwards, it was decided by the Government of India to withdraw the type 2 strain based on its epidemiological significance. So, a large number of children received the same strain that had been used under the National Immun...
Comments
Post a Comment